Publications as leading author or as principal investigator
[075] Tchitchek N, Binvignat M, Roux A, Pitoiset F, Dubois J, Marguerit G, Saadoun D, Cacoub P, Sellam J, Berenbaum F, Hartemann A, Amouyal C, Lorenzon R, Mariotti-Ferrandiz E, Rosenzwajg M, and Klatzmann D Ann Rheum Dis. (2024) "Deep immunophenotyping reveals that autoimmune and autoinflammatory disorders are spread along two immunological axes capturing disease inflammation levels and types." [068] Tchitchek N, Nguekap Tchoumba O, Pires G, Dandou S, Campagne J, Churlaud G, Fourcade G, Hoffmann TW, Strozzi F, Gaal C, Bonny C, Le Chatelier E, Erlich SD, Sokol H, and Klatzmann D JCI Insight. (2022) 7(17). "Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation." [055] Leite Pereira A, Jouhault Q, Marcos Lopez E, Cosma A, Lambotte O, Le Grand R, Lehmann MH, and Tchitchek N Front Immunol. (2020) 11:2096. "Modulation of Cell Surface Receptor Expression by Modified Vaccinia Virus Ankara in Leukocytes of Healthy and HIV-Infected Individuals." [046] Leite Pereira A, Bitoun S, Paoletti A, Nocturne G, Marcos Lopez E, Cosma A, Le Grand R, Mariette X, and Tchitchek N Front Immunol. (2019) 10:2384. "Characterization of Phenotypes and Functional Activities of Leukocytes From Rheumatoid Arthritis Patients by Mass Cytometry." [044] Leite Pereira A*, Tchitchek N*, Lambotte O, Le Grand R, and Cosma A Front Immunol. (2019) 10:1777. "Characterization of Leukocytes From HIV-ART Patients Using Combined Cytometric Profiles of 72 Cell Markers." [043] Nugeyre MT*, Tchitchek N*, Adapen C, Cannou C, Contreras V, Benjelloun F, Ravel J, Le Grand R, Marlin R, and Menu E Front Cell Infect Microbiol. (2019) 9:188. "Dynamics of Vaginal and Rectal Microbiota Over Several Menstrual Cycles in Female Cynomolgus Macaques." [039] Leite Pereira A, Lambotte O, Le Grand R, Cosma A, and Tchitchek N Bioinformatics. (2019) 35(20):4187-4189. "CytoBackBone: an algorithm for merging of phenotypic information from different cytometric profiles." [029] Platon L, Pejoski D, Gautreau G, Targat B, Le Grand R, Beignon AS, and Tchitchek N Methods. (2017) 132:66-75. "A computational approach for phenotypic comparisons of cell populations in high-dimensional cytometry data." [023] Gautreau G, Pejoski D, Le Grand R, Cosma A, Beignon AS, and Tchitchek N Bioinformatics. (2016) 33(5):779-781. "SPADEVizR: an R package for visualization, analysis and integration of SPADE results." [018] Herbert F*, Tchitchek N*, Bansal D, Jacques J, Pathak S, Bécavin C, Fesel C, Dalko E, Cazenave PA, Preda C, Ravindran B, Sharma S, Das B, and Pied S J Transl Med. (2015) 13:369. "Evidence of IL-17, IP-10, and IL-10 involvement in multiple-organ dysfunction and IL-17 pathway in acute renal failure associated to Plasmodium falciparum malaria." [017] Rasmussen AL*, Tchitchek N*, Safronetz D, Carter VS, Williams CM, Haddock E, Korth MJ, Feldmann H, and Katze MG J Virol. (2014) 89(5):2543-52. "Delayed inflammatory and cell death responses are associated with reduced pathogenicity in Lujo virus-infected cynomolgus macaques." [016] Tchitchek N, Safronetz D, Rasmussen AL, Martens C, Virtaneva K, Porcella SF, Feldmann H, Ebihara H, and Katze MG PLoS One. (2014) 9(11):e112617. "Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome." [011] Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, Baric R, Kawaoka Y, and Katze MG BMC Syst Biol. (2013) 7:69. "Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice." [007] Tchitchek N, Dzib JF, Targat B, Noth S, Benecke A, and Lesne A Genomics Proteomics Bioinformatics. (2012) 10(3):127-35. "CDS: a fold-change based statistical test for concomitant identification of distinctness and similarity in gene expression analysis." [006] Tchitchek N*, Jacquelin B*, Wincker P, Dossat C, Silva CD, Weissenbach J, Blancher A, Müller-Trutwin M, and Benecke A BMC Genomics. (2012) 13:279. "Expression sequence tag library derived from peripheral blood mononuclear cells of the chlorocebus sabaeus." [005] Rasmussen AL*, Tchitchek N*, Susnow NJ, Krasnoselsky AL, Diamond DL, Yeh MM, Proll SC, Korth MJ, Walters KA, Lederer S, Larson AM, Carithers RL, Benecke A, and Katze MG Hepatology. (2012) 56(1):17-27. "Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients."* These authors equaly contributed to the works
Publications from collaborative works
[074] Ellul P, Maruani A, Vantalon V, Humeau E, Amestoy A, Anchordoqui A, Atzori P, Baleyte JM, Benmansour S, Bonnot O, Bouvard M, Cartigny A, Coulon N, Coutelle R, Da Fonseca D, Demily C, Givaudan M, Gollier-Briant F, Guénolé F, Koch A, Leboyer M, Lefebvre A, Lejuste F, Levy C, Mendes E, Robert N, Schroder CM, Speranza M, Zante E, Peyre H, Rosenzwajg M, Klatzmann D, Tchitchek N, and Delorme R Sci Rep. (2023) 13(1):17687. "Maternal immune activation during pregnancy is associated with more difficulties in socio-adaptive behaviors in autism spectrum disorder." [073] Louapre C, Rosenzwajg M, Golse M, Roux A, Pitoiset F, Adda L, Tchitchek N, Papeix C, Maillart E, Ungureanu A, Charbonnier-Beaupel F, Galanaud D, Corvol JC, Vicaut E, Lubetzki C, and Klatzmann D J Neurol. (2023) 270(9):4403-4414. "A randomized double-blind placebo-controlled trial of low-dose interleukin-2 in relapsing-remitting multiple sclerosis." [072] Ellul P, Melki I, Antoun S, Lavialle L, Acquaviva E, Aeschlimann FA, Bader-Meunier B, Belot A, Dingulu G, Dumaine C, Faye A, Frémond ML, Meinzer U, Peyre H, Quartier P, Rosenzwajg M, Savioz I, Vinit C, Tchitchek N, Klatzmann D, and Delorme R Mol Psychiatry. (2023) 28(4):1516-1526. "Early systemic inflammation induces neurodevelopmental disorders: results from ARTEMIS, a French multicenter study of juvenile rheumatisms and systemic autoimmune and auto-inflammatory disorders and meta-analysis." [071] Binvignat M, Pires G, Tchitchek N, Costantino F, Courties A, Klatzmann D, Butte AJ, Combe B, Dougados M, Richette P, Mariotti-Ferrandiz E, Berenbaum F, and Sellam J Arthritis Care Res (Hoboken). (2022) 75(7):1494-1502. "Identification of Symptom Phenotypes of Hand Osteoarthritis Using Hierarchical Clustering: Results From the DIGICOD Cohort." [070] Flet-Berliac L, Tchitchek N, Lépine A, Florea A, Maurey H, Chrétien P, Hacein-Bey-Abina S, Villega F, Cheuret E, Rogemond V, Picard G, Honnorat J, and Deiva K Dev Med Child Neurol. (2022) 65(5):691-700. "Long-term outcome of paediatric anti-N-methyl-D-aspartate receptor encephalitis." [067] Dérian N, Pham HP, Nehar-Belaid D, Tchitchek N, Klatzmann D, Eric V, and Six A PLoS One. (2022) 17(4):e0266618. "The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets." [066] Monsel A, Hauw-Berlemont C, Mebarki M, Heming N, Mayaux J, Nguekap Tchoumba O, Diehl JL, Demoule A, Annane D, Marois C, Demeret S, Weiss E, Voiriot G, Fartoukh M, Constantin JM, Mégarbane B, Plantefève G, Malard-Castagnet S, Burrel S, Rosenzwajg M, Tchitchek N, Boucher-Pillet H, Churlaud G, Cras A, Maheux C, Pezzana C, Diallo MH, Ropers J, Menasché P, Larghero J Crit Care. (2022) 26(1):48. "Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial." [065] Feraoun Y, Palgen JL, Joly C, Tchitchek N, Marcos-Lopez E, Dereuddre-Bosquet N, Gallouet AS, Contreras V, Lévy Y, Martinon F, Le Grand R, and Beignon AS Front Immunol. (2022) 12:784813. "The Route of Vaccine Administration Determines Whether Blood Neutrophils Undergo Long-Term Phenotypic Modifications." [064] Jeger-Madiot R, Vaineau R, Heredia M, Tchitchek N, Bertrand L, Pereira M, Konza O, Gouritin B, Hoareau-Coudert B, Corneau A, Blanc C, Savier E, Buffet P, Six A, Klatzmann D, Moris A, and Graff-Dubois S iScience. (2022) 25(1):103566. "Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells." [063] Cavarelli M, Hua S, Hantour N, Tricot S, Tchitchek N, Gommet C, Hocini H, Chapon C, Dereuddre-Bosquet N, and Le Grand R Commun Biol. (2021) 4(1):861. "Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants." [061] Rosenbaum P, Tchitchek N, Joly C, Rodriguez Pozo A, Stimmer L, Langlois S, Hocini H, Gosse L, Pejoski D, Cosma A, Beignon AS, Dereuddre-Bosquet N, Levy Y, Le Grand R, and Martinon F Front Immunol. (2021) 12:645210. "Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response." [060] Huot N, Rascle P, Tchitchek N, Wimmer B, Passaes C, Contreras V, Desjardins D, Stahl-Hennig C, Le Grand R, Saez-Cirion A, Jacquelin B, and Müller-Trutwin M iScience. (2021) 24(4):102314. "Role of NKG2a/c+CD8+ T cells in pathogenic versus non-pathogenic SIV infections." [058] Rubino E, Cruciani M, Tchitchek N, Le Tortorec A, Rolland AD, Veli Ö, Vallet L, Gaggi G, Michel F, Dejucq-Rainsford N, and Pellegrini S Front Genet. (2021) 11:627007. "Human Ubiquitin-Specific Peptidase 18 Is Regulated by microRNAs via the 3'Untranslated Region, A Sequence Duplicated in Long Intergenic Non-coding RNA Genes Residing in chr22q11.21." [057] Jochems SP, Jacquelin B, Tchitchek N, Busato F, Pichon F, Huot N, Liu Y, Ploquin MJ, Roché E, Cheynier R, Dereuddre-Bosquet N, Stahl-Henning C, Le Grand R, Tost J, and Müller-Trutwin M Clin Epigenetics. (2020) 12(1):188. "DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections." [056] Rivière E, Pascaud J, Virone A, Dupré A, Ly B, Paoletti A, Seror R, Tchitchek N, Mingueneau M, Smith N, Duffy D, Cassard L, Chaput N, Pengam S, Gauttier V, Poirier N, Mariette X, and Nocturne G Arthritis Rheumatol. (2020) 73(4):631-640. "Interleukin-7/Interferon Axis Drives T Cell and Salivary Gland Epithelial Cell Interactions in Sjögren's Syndrome." [054] Danès L, Tchitchek N, and Bécavin C Bioinformatics. (2020) 37(9):1335-1336. "Bacnet: a user-friendly platform for building multi-omics websites." [053] Rivière E, Pascaud J, Tchitchek N, Boudaoud S, Paoletti A, Ly B, Dupré A, Chen H, Thai A, Allaire N, Jagla B, Mingueneau M, Nocturne G, and Mariette X Ann Rheum Dis. (2020) 79(11):1468-1477. "Salivary gland epithelial cells from patients with Sjögren's syndrome induce B-lymphocyte survival and activation." [052] Rosenzwajg M, Salet R, Lorenzon R, Tchitchek N, Roux A, Bernard C, Carel JC, Storey C, Polak M, Beltrand J, Amouyal C, Hartemann A, Corbeau P, Vicaut E, Bibal C, Bougnères P, Tran TA, and Klatzmann D Diabetologia. (2020) 63(9):1808-1821. "Low-dose IL-2 in children with recently diagnosed type 1 diabetes: a Phase I/II randomised, double-blind, placebo-controlled, dose-finding study." [051] Adam L, Tchitchek N, Todorova B, Rosenbaum P, Joly C, Poux C, Chapon C, Spetz AL, Ustav M, Le Grand R, and Martinon F J Immunol. (2020) 204(12):3375-3388. "Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination." [050] Palgen JL, Tchitchek N, Rodriguez-Pozo A, Jouhault Q, Abdelhouahab H, Dereuddre-Bosquet N, Contreras V, Martinon F, Cosma A, Lévy Y, Le Grand R, and Beignon AS NPJ Vaccines. (2020) 5(1):24. "Innate and secondary humoral responses are improved by increasing the time between MVA vaccine immunizations." [049] Gonnet J, Poncelet L, Meriaux C, Gonçalves E, Weiss L, Tchitchek N, Pedruzzi E, Soria A, Boccara D, Vogt A, Bonduelle O, Hamm G, Ait-Belkacem R, Stauber J, Fournier I, Wisztorski M, and Combadiere B J Proteomics. (2020) 216:103670. "Mechanisms of innate events during skin reaction following intradermal injection of seasonal influenza vaccine." [048] Coindre S, Tchitchek N, Alaoui L, Vaslin B, Bourgeois C, Goujard C, Lecuroux C, Bruhns P, Le Grand R, Beignon AS, Lambotte O, and Favier B Front Immunol. (2019) 10:2677. "Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection." [047] Serguera C, Stimmer L, Fovet CM, Horellou P, Contreras V, Tchitchek N, Massonneau J, Leroy C, Perrin A, Flament J, Hantraye P, Demilly J, Marignier R, Chrétien P, Hart B, Boutonnat J, Adam C, Le-Grand R, and Deiva K J Neuroinflammation. (2019) 16(1):244. "Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases." [045] Fovet CM, Stimmer L, Contreras V, Horellou P, Hubert A, Seddiki N, Chapon C, Tricot S, Leroy C, Flament J, Massonneau J, Tchitchek N, 't Hart BA, Zurawski S, Klucar P, Hantraye P, Deiva K, Zurawski G, Oh S, Le Grand R, and Serguera C EBioMedicine. (2019) 47:492-505. "Intradermal vaccination prevents anti-MOG autoimmune encephalomyelitis in macaques." [042] Shiina T, Suzuki S, Congy-Jolivet N, Aarnink A, Garchon HJ, Dereuddre-Bosquet N, Vaslin B, Tchitchek N, Desjardins D, Autran B, Lambotte O, Theodorou I, Le Grand R, and Blancher A Sci Rep. (2019) 9(1):7981. "Cynomolgus macaque IL37 polymorphism and control of SIV infection." [041] Mauffrey P, Tchitchek N, Barroca V, Bemelmans AP, Firlej V, Allory Y, Roméo PH, and Magnon C Nature. (2019) 569(7758):672-678. "Progenitors from the central nervous system drive neurogenesis in cancer." [040] Marlin R, Nugeyre MT, Tchitchek N, Parenti M, Lefebvre C, Hocini H, Benjelloun F, Cannou C, Nozza S, Dereuddre-Bosquet N, Levy Y, Barré-Sinoussi F, Scarlatti G, Le Grand R, and Menu E Front Immunol. (2019) 10:430. "Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae." [038] Tissier R, Hocini H, Tchitchek N, Deye N, Legriel S, Pichon N, Daubin C, Hermine O, Carli P, Vivien B, Tréluyer JM, Lefebvre C, Tisserand P, Dubois-Randé JL, Berdeaux A, Ghaleh B, Lelièvre JD, Levy Y, and Cariou A Resuscitation. (2019) 138:222-232. "Early blood transcriptomic signature predicts patients' outcome after out-of-hospital cardiac arrest." [037] Gonçalves E, Bonduelle O, Soria A, Loulergue P, Rousseau A, Cachanado M, Bonnabau H, Thiebaut R, Tchitchek N, Behillil S, van der Werf S, Vogt A, Simon T, Launay O, and Combadière B J Clin Invest. (2019) 129(5):1960-1971. "Innate gene signature distinguishes humoral versus cytotoxic responses to influenza vaccination." [036] Palgen JL, Tchitchek N, Huot N, Elhmouzi-Younes J, Lefebvre C, Rosenbaum P, Dereuddre-Bosquet N, Martinon F, Hocini H, Cosma A, Müller-Trutwin M, Lévy Y, Le Grand R, and Beignon AS J Leukoc Biol. (2019) 105(5):1055-1073. "NK cell immune responses differ after prime and boost vaccination." [035] Leite Pereira A, Tchitchek N, Marcos Lopez E, Lambotte O, Le Grand R, and Cosma A Cytokine. (2018) 111:97-105. "A high-resolution mass cytometry analysis reveals a delay of cytokines production after TLR4 or TLR7/8 engagements in HIV-1 infected humans." [034] Rosenbaum P, Tchitchek N, Joly C, Stimmer L, Hocini H, Dereuddre-Bosquet N, Beignon AS, Chapon C, Levy Y, Le Grand R, and Martinon F Front Immunol. (2018) 9:870. "Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine." [033] Coindre S, Tchitchek N, Alaoui L, Vaslin B, Bourgeois C, Goujard C, Avettand-Fenoel V, Lecuroux C, Bruhns P, Le Grand R, Beignon AS, Lambotte O, Favier B Front Immunol. (2018) 9:1217. "Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a+ CD4+ T Cells From Early HIV Infection to Effective cART." [032] Palgen JL, Tchitchek N, Elhmouzi-Younes J, Delandre S, Namet I, Rosenbaum P, Dereuddre-Bosquet N, Martinon F, Cosma A, Lévy Y, Le Grand R, and Beignon AS Sci Rep. (2018) 8(1):3087. "Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response." [031] Echebli N, Tchitchek N, Dupuy S, Bruel T, Peireira Bittencourt Passaes C, Bosquet N, Le Grand R, Bourgeois C, Favier B, Cheynier R, Lambotte O, and Vaslin B PLoS One. (2018) 13(1):e0190334. "Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection." [028] Marlin R, Nugeyre MT, Tchitchek N, Parenti M, Hocini H, Benjelloun F, Cannou C, Dereuddre-Bosquet N, Levy Y, Barré-Sinoussi F, Scarlatti G, Le Grand R, and Menu E J Immunol. (2017) 199(5):1923-1932. "Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry." [027] Elhmouzi-Younes J, Palgen JL, Tchitchek N, Delandre S, Namet I, Bodinham CL, Pizzoferro K, Lewis DJM, Le Grand R, Cosma A, and Beignon AS Cytometry A. (2017) 91(10):969-982. "In depth comparative phenotyping of blood innate myeloid leukocytes from healthy humans and macaques using mass cytometry." [026] Roques P, Ljungberg K, Kümmerer BM, Gosse L, Dereuddre-Bosquet N, Tchitchek N, Hallengärd D, García-Arriaza J, Meinke A, Esteban M, Merits A, Le Grand R, and Liljeström P JCI Insight. (2017) 2(6):e83527. "Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus." [025] Bécavin C, Koutero M, Tchitchek N, Cerutti F, Lechat P, Maillet N, Hoede C, Chiapello H, Gaspin C, and Cossart P mSystems. (2017) 2(2). "Listeriomics: an Interactive Web Platform for Systems Biology of Listeria." [024] Lamart S, Griffiths NM, Tchitchek N, Angulo JF, and Van der Meeren A J Radiol Prot. (2017) 37(1):296-308. "Analysis methodology and development of a statistical tool for biodistribution data from internal contamination with actinides." [022] Bodez D, Hocini H, Tchitchek N, Tisserand P, Benhaiem N, Barau C, Kharoubi M, Guellich A, Guendouz S, Radu C, Couetil JP, Ghaleh B, Dubois-Randé JL, Teiger E, Hittinger L, Levy Y, and Damy T PLoS One. (2016) 11(11):e0167213. "Myocardial Gene Expression Profiling to Predict and Identify Cardiac Allograft Acute Cellular Rejection: The GET-Study." [021] Dalko E, Tchitchek N, Pays L, Herbert F, Cazenave PA, Ravindran B, Sharma S, Nataf S, Das B, and Pied S PLoS One. (2016) 11(7):e0158420. "Erythropoietin Levels Increase during Cerebral Malaria and Correlate with Heme, Interleukin-10 and Tumor Necrosis Factor-Alpha in India." [020] Pejoski D, Tchitchek N, Rodriguez Pozo A, Elhmouzi-Younes J, Yousfi-Bogniaho R, Rogez-Kreuz C, Clayette P, Dereuddre-Bosquet N, Lévy Y, Cosma A, Le Grand R, and Beignon AS J Immunol. (2016) 196(11):4814-31. "Identification of Vaccine-Altered Circulating B Cell Phenotypes Using Mass Cytometry and a Two-Step Clustering Analysis." [019] Forero A, Tisoncik-Go J, Watanabe T, Zhong G, Hatta M, Tchitchek N, Selinger C, Chang J, Barker K, Morrison J, Berndt JD, Moon RT, Josset L, Kawaoka Y, and Katze MG J Virol. (2015) 90(5):2240-53. "The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice." [015] Morrison J, Josset L, Tchitchek N, Chang J, Belser JA, Swayne DE, Pantin-Jackwood MJ, Tumpey TM, and Katze MG J Virol. (2014) 88(18):10556-68. "H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice." [014] Josset L, Tchitchek N, Gralinski LE, Ferris MT, Eisfeld AJ, Green RR, Thomas MJ, Tisoncik-Go J, Schroth GP, Kawaoka Y, Manuel de Villena FP, Baric RS, Heise MT, Peng X, and Katze MG RNA Biol. (2014) 11(7):875-90. "Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts." [013] Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kaiser SM, Kelly S, Law GL, Li C, Li J, Long C, Luna ML, Matzke M, McDermott J, Menachery V, Metz TO, Mitchell H, Monroe ME, Navarro G, Neumann G, Podyminogin RL, Purvine SO, Rosenberger CM, Sanders CJ, Schepmoes AA, Shukla AK, Sims A, Sova P, Tam VC, Tchitchek N, Thomas PG, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Aderem A, Katze MG, and Scheuermann RH Sci Data. (2014) 1:140033. "A comprehensive collection of systems biology data characterizing the host response to viral infection." [012] Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, Shukla AK, Metz TO, Neumann G, Benecke AG, Smith RD, Baric RS, Kawaoka Y, Katze MG, and Waters KM PLoS One. (2013) 8(7):e69374. "A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses." [010] Watanabe T, Tisoncik-Go J, Tchitchek N, Watanabe S, Benecke AG, Katze MG, and Kawaoka Y J Virol. (2013) 87(9):5239-54. "1918 Influenza virus hemagglutinin (HA) and the viral RNA polymerase complex enhance viral pathogenicity, but only HA induces aberrant host responses in mice." [008] Go JT, Belisle SE, Tchitchek N, Tumpey TM, Ma W, Richt JA, Safronetz D, Feldmann H, and Katze MG BMC Genomics. (2012) 13:627. "2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models." [004] Chang ST, Tchitchek N, Ghosh D, Benecke A, and Katze MG BMC Syst Biol. (2011) 5:202. "A chemokine gene expression signature derived from meta-analysis predicts the pathogenicity of viral respiratory infections." [003] Bécavin C, Tchitchek N, Mintsa-Eya C, Lesne A, and Benecke A Bioinformatics. (2011) 27(10):1413-21. "Improving the efficiency of multidimensional scaling in the analysis of high-dimensional data using singular value decomposition." [002] Fernandes-Rosa FL, Hubert EL, Fagart J, Tchitchek N, Gomes D, Jouanno E, Benecke A, Rafestin-Oblin ME, Jeunemaitre X, Antonini SR, and Zennaro MC J Clin Endocrinol Metab. (2010) 96(3):E519-27. "Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1." [001] Endt K, Stecher B, Chaffron S, Slack E, Tchitchek N, Benecke A, Van Maele L, Sirard JC, Mueller AJ, Heikenwalder M, Macpherson AJ, Strugnell R, von Mering C, and Hardt WD PLoS Pathog. (2010) 6(9):e1001097. "The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea."Reviews, book chapters, and editorials
[069] Dirheimer M, Ducancel F, Savatier P, Tchitchek N, Vecellio-None L Manuel d’expérimentation animale; Presses Universitaires François-Rabelais. (2022) 1(1):. ISBN-13 : 978-2-86906-886-5. "Perspectives de l’expérimentation animale: Principes généraux." [062] Van Tilbeurgh M, Lemdani K, Beignon AS, Chapon C, Tchitchek N, Cheraitia L, Marcos Lopez E, Pascal Q, Le Grand R, Maisonnasse P, and Manet C Vaccines (Basel). (2021) 9(6). "Predictive Markers of Immunogenicity and Efficacy for Human Vaccines." [059] Tchitchek N and Le Bescop C La cytométrie en flux (2° édition); Tec & Doc Lavoisier. (2020) 2(1):233-241. ISBN-13 : 978-2743024901. "L’analyse de données cytométriques de grande dimension." [030] Tchitchek N Methods. (2017) 132:1-2. "Navigating in the vast and deep oceans of high-dimensional biological data." [009] Korth MJ, Tchitchek N, Benecke AG, and Katze MG Semin Immunol. (2012) 25(3):228-39. "Systems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic viruses."Other links to my list of publications
My list of publications and the associated papers can also be obtained at: